Cetyl Alcohol
FDA-approved product (for suspension, intratracheal).
- Registered studies
- 29
- Lab records
- 1
- Pathogens at ≥40%
- 0 of 4
Chemical structure
Existing / approved use
Documented · FDA, WHO, ChEMBLNo approved indication recorded
ChEMBL records no approved indication for Cetyl Alcohol. Its therapeutic class is shown instead.
- Anti-infective classification
- Neither a WHO ATC code nor an FDA pharmacologic class was found for it, so whether it is already an antimicrobial is not established. It needs review and is not counted as a repurposing candidate.
Repurposing investigation
No supported pathogen reaches ≥40% AI-predicted activity for Cetyl Alcohol, so it is not among the repurposing candidates. Its predictions are shown below.
AI-predicted activity
AI prediction · nothing measured- MRSA12.3% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates. This medicine was in the model's training data, so this is recall, not a new prediction.
- E. coli3.2% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.
- K. pneumoniae7.6% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.
- M. tuberculosis6.3% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.
A model’s estimate of laboratory activity against each pathogen species. It is not clinical effectiveness.
Evidence
Clinical and experimental
Documented evidenceClinical
29registered studies name this medicine, for any condition. See them below.
Experimental
- MRSA: measured active in 0 of 1 lab record
Show the 1 laboratory record, with sources
Loading records…
“Active” means the measured value reached this project’s laboratory cutoff (10 µM or stronger). A laboratory result does not show an effect in patients.
Docking
Computational · nothing measuredDihydrofolate reductase ↗ (E. coli)
Not yet docked: queued in the docking rundetails
KPC-2 carbapenemase ↗ (K. pneumoniae)
Not yet docked: queued in the docking rundetails
Enoyl-ACP reductase (InhA) ↗ (M. tuberculosis)
Not yet docked: queued in the docking rundetails
Dihydrofolate reductase ↗ (MRSA)
Not yet docked: queued in the docking rundetails
AutoDock Vina, one experimentally solved protein per pathogen. This project’s screening target is -7.0 kcal/mol, its own mark rather than a universal cutoff. A docking score is a structural hypothesis, not proof of binding, and requires experimental validation.
Other medicines to investigate
AI prediction · nothing measuredOther repurposing candidates: approved medicines besides Cetyl Alcohol with AI-predicted activity ≥40% against the chosen pathogen, leaving out existing antimicrobials. They are computational candidates for further investigation, not alternatives and not recommendations.
Sorted by AI-predicted activity, high to low. The order is not a ranking of which medicine is better.
- Mefloquine HydrochlorideExisting use: Malaria, Plasmodium falciparum malaria, Plasmodium vivax malaria81.8% AI-predicted activityagainst M. tuberculosisLab records exist8 registered studies
- KetoconazoleExisting use: Adrenal gland disease, Blastomycosis, Cushing syndrome and 3 more81.2% AI-predicted activityagainst M. tuberculosisLab records exist50+ registered studies
- LevoketoconazoleExisting use: Adrenal gland disease, Adrenal gland hyperfunction, Cushing syndrome81.2% AI-predicted activityagainst M. tuberculosis6 registered studies
- Fluphenazine DecanoateExisting use: Mental or behavioural disorder, Psychosis80.7% AI-predicted activityagainst M. tuberculosis4 registered studies
- Fluphenazine EnanthateExisting use: Mental or behavioural disorder, Psychosis80.7% AI-predicted activityagainst M. tuberculosisNo documented evidence found
- NifurtimoxExisting use: American trypanosomiasis, Chagas disease, Leishmaniasis and 1 more78.4% AI-predicted activityagainst M. tuberculosis19 registered studies
- Fluphenazine HydrochlorideExisting use: Mental or behavioural disorder, Psychosis77.8% AI-predicted activityagainst M. tuberculosis5 registered studies
- NitazoxanideExisting use: Amebiasis, Diarrhea77.8% AI-predicted activityagainst M. tuberculosisLab records exist50+ registered studies
- TopiramateExisting use: Epilepsy, Lennox-Gastaut syndrome, Migraine disorder and 1 more77.4% AI-predicted activityagainst M. tuberculosisLab records exist50+ registered studies
- TrabectedinExisting use: Cancer, Dedifferentiated liposarcoma, Leiomyosarcoma and 7 more76.8% AI-predicted activityagainst M. tuberculosis50+ registered studies
- Chlorpromazine HydrochlorideExisting use: Conduct disorder, Mental or behavioural disorder, Nausea and vomiting and 3 more75.0% AI-predicted activityagainst M. tuberculosis33 registered studies
- ProchlorperazineExisting use: Anxiety disorder, Nausea and vomiting, Psychosis and 1 more74.1% AI-predicted activityagainst M. tuberculosis50+ registered studies
Registered studies
A registration describes a study; it does not establish a positive result.
A Clinical Study to Assess Efficacy and Tolerability of a Topical Skincare Product on Adults With Mature, Crepey Skin
NCT07398989 · start 2025-08-12
Registered record
- Registry ID
- NCT07398989
- Conditions
- Crepey Skin; Aging Skin; Photo-aged Skin
- Interventions
- Cetaphil
- Study type
- INTERVENTIONAL
- Phase
- Phase 4
- Registry status
- Completed
- Start
- 2025-08-12
- Completion
- 2026-03-25
- Enrolment
- 32
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionCrepey Skin; Aging Skin; Photo-aged SkinInterventionCetaphilPhasePhase 4Registry statusCompletedSkin Barrier Function and Inflammation in Aging: The BIA Study
NCT06750653 · start 2025-02-06
Registered record
- Registry ID
- NCT06750653
- Conditions
- Inflammation; Skin Inflammation; Aging
- Interventions
- CeraVe Moisturizing Cream; Vaseline
- Study type
- INTERVENTIONAL
- Phase
- Phase 4
- Registry status
- Completed
- Start
- 2025-02-06
- Completion
- 2026-04-02
- Enrolment
- 32
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionInflammation; Skin Inflammation; AgingInterventionCeraVe Moisturizing Cream; VaselinePhasePhase 4Registry statusCompletedA Study to Assess Efficacy and Tolerability of Topical Skincare Products on Psoriasis Patients
NCT06357221 · start 2024-04-08
Registered record
- Registry ID
- NCT06357221
- Conditions
- Plaque Psoriasis; Psoriasis
- Interventions
- Cetaphil
- Study type
- INTERVENTIONAL
- Phase
- Phase 4
- Registry status
- Completed
- Start
- 2024-04-08
- Completion
- 2024-07-18
- Enrolment
- 46
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionPlaque Psoriasis; PsoriasisInterventionCetaphilPhasePhase 4Registry statusCompletedA Single Group Study to Evaluate the Efficacy of a Cosmetic Product Line on Acne Symptoms
NCT06122467 · start 2023-10-02
Registered record
- Registry ID
- NCT06122467
- Conditions
- Acne
- Interventions
- EQ Exfoliating Cleanser; EQ Gel; EQ Moisturizer
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2023-10-02
- Completion
- 2023-12-31
- Enrolment
- 36
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionAcneInterventionEQ Exfoliating Cleanser; EQ Gel; EQ MoisturizerPhaseNot applicableRegistry statusCompletedA Comparative Split-Face Study of the Effects of a Retinol Alternative Cream on Improving Facial Skin Aging
NCT06125912 · start 2023-09-25
Registered record
- Registry ID
- NCT06125912
- Conditions
- Skin Aging
- Interventions
- Dime Beauty TBT Cream; Positive Control
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2023-09-25
- Completion
- 2024-02-15
- Enrolment
- 35
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionSkin AgingInterventionDime Beauty TBT Cream; Positive ControlPhaseNot applicableRegistry statusCompletedA Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity
NCT06146712 · start 2023-08-07
Registered record
- Registry ID
- NCT06146712
- Conditions
- Sleep
- Interventions
- Asutra's 'Dream the night away' nighttime lotion
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2023-08-07
- Completion
- 2023-10-02
- Enrolment
- 35
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionSleepInterventionAsutra's 'Dream the night away' nighttime lotionPhaseNot applicableRegistry statusCompletedDevelopment of a Protective Cream Against Radiodermatitis Caused by Radiotherapy.
NCT05886673 · start 2023-03-29
Registered record
- Registry ID
- NCT05886673
- Conditions
- Radiodermatitis
- Interventions
- experimental cream; standard of care
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Unknown
- Start
- 2023-03-29
- Completion
- 2023-12
- Enrolment
- 5
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionRadiodermatitisInterventionexperimental cream; standard of carePhaseNot applicableRegistry statusUnknownA Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum
NCT05514782 · start 2021-09-15
Registered record
- Registry ID
- NCT05514782
- Conditions
- Photoaging; Wrinkle
- Interventions
- Cleansing Lotion; Facial Moisturizer; Sunscreen SPF 40+
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2021-09-15
- Completion
- 2021-12-10
- Enrolment
- 67
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionPhotoaging; WrinkleInterventionCleansing Lotion; Facial Moisturizer; Sunscreen SPF 40+PhaseNot applicableRegistry statusCompletedColloidal Oatmeal, Colloid Cream, Diaper Rash, Preterm Neonates and Neonatal Intensive Care Unit
NCT05892081 · start 2021-08-20
Registered record
- Registry ID
- NCT05892081
- Conditions
- Diaper Rash; Preterm Neonates
- Interventions
- Colloidal oatmeal; Cold cream
- Study type
- INTERVENTIONAL
- Phase
- Phase 4
- Registry status
- Completed
- Start
- 2021-08-20
- Completion
- 2023-08-30
- Enrolment
- 90
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionDiaper Rash; Preterm NeonatesInterventionColloidal oatmeal; Cold creamPhasePhase 4Registry statusCompletedEfficacy of Topical Antioxidants in Tretment of Photoaging
NCT04835259 · start 2021-04
Registered record
- Registry ID
- NCT04835259
- Conditions
- Photoaging
- Interventions
- Selenium Amino Acid Chelate (Selenium ACE cream)
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Unknown
- Start
- 2021-04
- Completion
- 2022-06
- Enrolment
- 90
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionPhotoagingInterventionSelenium Amino Acid Chelate (Selenium ACE cream)PhaseNot applicableRegistry statusUnknownA Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum
NCT05271136 · start 2020-09-30
Registered record
- Registry ID
- NCT05271136
- Conditions
- Fine Lines; Wrinkle; Photoaging
- Interventions
- Anti-aging Serum; Facial Moisturizer; Cleansing Lotion; Sunscreen; Sunscreen
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2020-09-30
- Completion
- 2020-10-13
- Enrolment
- 26
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionFine Lines; Wrinkle; PhotoagingInterventionAnti-aging Serum; Facial Moisturizer; Cleansing Lotion; Sunscreen +1 morePhaseNot applicableRegistry statusCompletedStudy of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy
NCT04173247 · start 2020-07-27
Registered record
- Registry ID
- NCT04173247
- Conditions
- Head and Neck Cancer; Radiation Dermatitis
- Interventions
- KeraStat Cream; Routine Skin Care - Commercially Available Agents
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2020-07-27
- Completion
- 2022-10-07
- Enrolment
- 28
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionHead and Neck Cancer; Radiation DermatitisInterventionKeraStat Cream; Routine Skin Care - Commercially Available AgentsPhaseNot applicableRegistry statusCompletedTopical and Oral Regimen for Skin Health
NCT04872946 · start 2019-11-26
Registered record
- Registry ID
- NCT04872946
- Conditions
- Skin Abnormalities
- Interventions
- Tea; Serum; Moisturizer
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2019-11-26
- Completion
- 2020-05-07
- Enrolment
- 74
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionSkin AbnormalitiesInterventionTea; Serum; MoisturizerPhaseNot applicableRegistry statusCompletedEfficacy Evaluation of the Probiotics Containing Skincare Products on Skin
NCT03350893 · start 2017-09-18
Registered record
- Registry ID
- NCT03350893
- Conditions
- Skin Problems
- Interventions
- Emulsion base with probiotics; Emulsion base
- Study type
- INTERVENTIONAL
- Phase
- Not applicable
- Registry status
- Completed
- Start
- 2017-09-18
- Completion
- 2018-08-31
- Enrolment
- 20
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionSkin ProblemsInterventionEmulsion base with probiotics; Emulsion basePhaseNot applicableRegistry statusCompletedEffects of 2% IDL Lotion on Skin Hydration and Transepidermal Water Loss in Females With Dry Skin
NCT04253704 · start 2017-02-13
Registered record
- Registry ID
- NCT04253704
- Conditions
- Xerosis Cutis
- Interventions
- IDL lotion; Control lotion
- Study type
- INTERVENTIONAL
- Phase
- Phase 1 / Phase 2
- Registry status
- Completed
- Start
- 2017-02-13
- Completion
- 2017-03-03
- Enrolment
- 16
As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.
ConditionXerosis CutisInterventionIDL lotion; Control lotionPhasePhase 1 / Phase 2Registry statusCompleted