Skip to content
AMR Drug RepurposingSmart Screeningresearch prototype

Tannic Acid

FDA-approved product (injectable, injection).

Registered studies
50+
Lab records
0
Pathogens at ≥40%
1 of 4

Chemical structure

Chemical structure of Tannic Acid
A drawing shows what the molecule is, not what it does.

Existing / approved use

Documented · FDA, WHO, ChEMBL

No approved indication recorded

ChEMBL records no approved indication for Tannic Acid. Its therapeutic class is shown instead.

Anti-infective classification
Neither a WHO ATC code nor an FDA pharmacologic class was found for it, so whether it is already an antimicrobial is not established. It needs review and is not counted as a repurposing candidate.

Repurposing investigation

Tannic Acid reaches ≥40% AI-predicted activity against MRSA, but no WHO ATC code or FDA pharmacologic class says whether it is already an antimicrobial. It needs review, so it is not counted among the repurposing candidates.

AI-predicted activity

AI prediction · nothing measured
  • MRSA42.5% AI-predicted activityAt or above the ≥40% mark this site uses to surface candidates.
  • E. coli27.3% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.
  • K. pneumoniae22.6% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.
  • M. tuberculosis34.5% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.

A model’s estimate of laboratory activity against each pathogen species. It is not clinical effectiveness.

Evidence

Clinical and experimental

Documented evidence

Clinical

50+registered studies name this medicine, for any condition. The registry search keeps the first 50, so there may be more. See them below.

Experimental

No evidence found

No laboratory measurement against the four pathogens in the ChEMBL records loaded here.

Open Tannic Acid in ChEMBL Registered studies below

Docking

Computational · nothing measured

Dihydrofolate reductase ↗ (E. coli)

Not yet docked: queued in the docking rundetails

KPC-2 carbapenemase ↗ (K. pneumoniae)

Not yet docked: queued in the docking rundetails

Enoyl-ACP reductase (InhA) ↗ (M. tuberculosis)

Not yet docked: queued in the docking rundetails

Dihydrofolate reductase ↗ (MRSA)

Not yet docked: queued in the docking rundetails

AutoDock Vina, one experimentally solved protein per pathogen. This project’s screening target is -7.0 kcal/mol, its own mark rather than a universal cutoff. A docking score is a structural hypothesis, not proof of binding, and requires experimental validation.

Other medicines to investigate

AI prediction · nothing measured

Other repurposing candidates: approved medicines besides Tannic Acid with AI-predicted activity ≥40% against the chosen pathogen, leaving out existing antimicrobials. They are computational candidates for further investigation, not alternatives and not recommendations.

Sorted by AI-predicted activity, high to low. The order is not a ranking of which medicine is better.

Registered studies

A registration describes a study; it does not establish a positive result.

  • Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects.

    NCT03234452 · start 2016-03-23

    Registered record
    Registry ID
    NCT03234452
    Conditions
    Disbiosis; Abdominal Pain; Constipation; Diarrhea; Stress
    Interventions
    Lactoflorene plus; Placebo Lactoflorene plus
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2016-03-23
    Completion
    2017-04-18
    Enrolment
    50

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionDisbiosis; Abdominal Pain; Constipation; Diarrhea +1 more
    InterventionLactoflorene plus; Placebo Lactoflorene plus
    PhaseNot applicable
    Registry statusCompleted

  • Comparison of Two Nutrition Interventions in Young Children in El Salvador

    NCT02567981 · start 2015-09

    Registered record
    Registry ID
    NCT02567981
    Conditions
    Micronutrient Deficiency
    Interventions
    21 micronutrient-fortified supplement; Cereal Fortificado (Fortified Cereal); Ferrous sulphate; Vitamin A
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Unknown
    Start
    2015-09
    Completion
    2020-09
    Enrolment
    4,577

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionMicronutrient Deficiency
    Intervention21 micronutrient-fortified supplement; Cereal Fortificado (Fortified Cereal); Ferrous sulphate; Vitamin A
    PhaseNot applicable
    Registry statusUnknown

  • Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome.

    NCT02031289 · start 2013-12

    Registered record
    Registry ID
    NCT02031289
    Conditions
    Anemia; Iron Deficiency
    Interventions
    Erythropoietin/Ferric carboxymaltose/Vitamin B12/Folic Acid
    Study type
    INTERVENTIONAL
    Phase
    Phase 4
    Registry status
    Completed
    Start
    2013-12
    Completion
    2018-05
    Enrolment
    1,003

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionAnemia; Iron Deficiency
    InterventionErythropoietin/Ferric carboxymaltose/Vitamin B12/Folic Acid
    PhasePhase 4
    Registry statusCompleted

  • Mother-caregivers of Children With Duchenne Muscular Dystrophy

    NCT01921374 · start 2013-08

    Registered record
    Registry ID
    NCT01921374
    Conditions
    Other Diseases or Conditions
    Interventions
    sleep parameters; Hormonal profile; Inflammatory profile; Cardiovascular profile; Metabolic profile
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2013-08
    Completion
    2014-07
    Enrolment
    60

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionOther Diseases or Conditions
    Interventionsleep parameters; Hormonal profile; Inflammatory profile; Cardiovascular profile +1 more
    PhaseNot applicable
    Registry statusCompleted

  • A Retrospective Analysis of Cerefolin NAC® in Cognitively Impaired Patients

    NCT01594541 · start 2013-01

    Registered record
    Registry ID
    NCT01594541
    Conditions
    Mild Cognitive Impairment
    Interventions
    Not recorded
    Study type
    OBSERVATIONAL
    Phase
    Not recorded
    Registry status
    Unknown
    Start
    2013-01
    Completion
    2014-04
    Enrolment
    700

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionMild Cognitive Impairment
    InterventionNot recorded
    PhaseNot recorded
    Registry statusUnknown

  • Cervical Preparation Before Dilation and Evacuation

    NCT01751087 · start 2013-01

    Registered record
    Registry ID
    NCT01751087
    Conditions
    Abortion, Induced
    Interventions
    Mifepristone; misoprostol; Osmotic dilators; placebo; placebo
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2013-01
    Completion
    2014-06
    Enrolment
    300

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionAbortion, Induced
    InterventionMifepristone; misoprostol; Osmotic dilators; placebo +1 more
    PhaseNot applicable
    Registry statusCompleted

  • Effect of Cerefolin®/CerefolinNAC® on Biomarker Measurements

    NCT01745198 · start 2012-12

    Registered record
    Registry ID
    NCT01745198
    Conditions
    Mild Cognitive Impairment; Alzheimer's Disease; Alzheimer's Disease Related Disorders
    Interventions
    Not recorded
    Study type
    OBSERVATIONAL
    Phase
    Not recorded
    Registry status
    Completed
    Start
    2012-12
    Completion
    2014-06
    Enrolment
    121

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionMild Cognitive Impairment; Alzheimer's Disease; Alzheimer's Disease Related Disorders
    InterventionNot recorded
    PhaseNot recorded
    Registry statusCompleted

  • Trace Element Replenishment Study in Hemodialysis Patients

    NCT01473914 · start 2012-11

    Registered record
    Registry ID
    NCT01473914
    Conditions
    End Stage Renal Disease
    Interventions
    Low dose: supplemental zinc, selenium and vitamin E; Standard renal vitamin: B and C renal vitamin; Medium dose: supplemental zinc, selenium and vitamin E
    Study type
    INTERVENTIONAL
    Phase
    Phase 3
    Registry status
    Completed
    Start
    2012-11
    Completion
    2014-01
    Enrolment
    150

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionEnd Stage Renal Disease
    InterventionLow dose: supplemental zinc, selenium and vitamin E; Standard renal vitamin: B and C renal vitamin; Medium dose: supplemental zinc, selenium and vitamin E
    PhasePhase 3
    Registry statusCompleted

  • A Nutritional Intervention for Diabetic Neuropathy

    NCT01690962 · start 2012-11

    Registered record
    Registry ID
    NCT01690962
    Conditions
    Diabetic Neuropathy
    Interventions
    Vegan diet and vitamin B12 supplement; Vitamin B12 supplement
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2012-11
    Completion
    2014-02
    Enrolment
    15

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionDiabetic Neuropathy
    InterventionVegan diet and vitamin B12 supplement; Vitamin B12 supplement
    PhaseNot applicable
    Registry statusCompleted

  • To Evaluate the Efficacy and Safety of Vitamin B12 Contains Extract of Lamb's Stomach in Treatment of Chronic Atrophic Gastritis (CAG)

    NCT01474044 · start 2011-08

    Registered record
    Registry ID
    NCT01474044
    Conditions
    Chronic Atrophic Gastritis (CAG)
    Interventions
    Gastropylor Complex Capsules; Placebo Comparator
    Study type
    INTERVENTIONAL
    Phase
    Phase 4
    Registry status
    Completed
    Start
    2011-08
    Completion
    2013-02
    Enrolment
    851

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionChronic Atrophic Gastritis (CAG)
    InterventionGastropylor Complex Capsules; Placebo Comparator
    PhasePhase 4
    Registry statusCompleted

  • A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer

    NCT01057589 · start 2010-02

    Registered record
    Registry ID
    NCT01057589
    Conditions
    Head and Neck Neoplasms
    Interventions
    Pemetrexed; Cetuximab; Cisplatin; Folic Acid; Vitamin B12
    Study type
    INTERVENTIONAL
    Phase
    Phase 2
    Registry status
    Completed
    Start
    2010-02
    Completion
    2012-10
    Enrolment
    66

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionHead and Neck Neoplasms
    InterventionPemetrexed; Cetuximab; Cisplatin; Folic Acid +1 more
    PhasePhase 2
    Registry statusCompleted

  • Effect of 1 Year Vitamin D or D Plus B-vitamins on Bone Markers in Elderly People (KnoVIB)

    NCT02586181 · start 2009-08

    Registered record
    Registry ID
    NCT02586181
    Conditions
    Nutritional Supplement Toxicity
    Interventions
    Vitamin D and Calcium; Vitamin D, Calcium, Vitamins B9, B6, B12
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2009-08
    Completion
    2011-07
    Enrolment
    93

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionNutritional Supplement Toxicity
    InterventionVitamin D and Calcium; Vitamin D, Calcium, Vitamins B9, B6, B12
    PhaseNot applicable
    Registry statusCompleted

  • Micronutrient Supplementation in in Paediatric Pulmonary Tuberculosis

    NCT00801606 · start 2008-12

    Registered record
    Registry ID
    NCT00801606
    Conditions
    Tuberculosis
    Interventions
    Zinc; Micronutrient without zinc; Micronutrient with zinc; Placebo
    Study type
    INTERVENTIONAL
    Phase
    Phase 3
    Registry status
    Completed
    Start
    2008-12
    Completion
    2012-06
    Enrolment
    403

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionTuberculosis
    InterventionZinc; Micronutrient without zinc; Micronutrient with zinc; Placebo
    PhasePhase 3
    Registry statusCompleted

  • Cobalamin Status in Young Children With Gastrointestinal Symptoms or Feeding Problems

    NCT00710359 · start 2008-04

    Registered record
    Registry ID
    NCT00710359
    Conditions
    Vitamin B 12 Deficiency
    Interventions
    Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2008-04
    Completion
    2010-08
    Enrolment
    100

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionVitamin B 12 Deficiency
    InterventionHydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
    PhaseNot applicable
    Registry statusCompleted

  • A Trial of Vitamins and HAART in HIV Disease Progression

    NCT00383669 · start 2006-11

    Registered record
    Registry ID
    NCT00383669
    Conditions
    HIV Infections
    Interventions
    Multivitamins (including B, C and E); Multivitamins B, C and E
    Study type
    INTERVENTIONAL
    Phase
    Phase 3
    Registry status
    Completed
    Start
    2006-11
    Completion
    2009-10
    Enrolment
    4,012

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionHIV Infections
    InterventionMultivitamins (including B, C and E); Multivitamins B, C and E
    PhasePhase 3
    Registry statusCompleted