Skip to content
AMR Drug RepurposingSmart Screeningresearch prototype

Triamcinolone Diacetate

FDA-approved product (injectable, injection), marketed as Aristocort, Kenacort, Triamcinolone Diacetate.

Registered studies
50+
Lab records
0
Pathogens at ≥40%
1 of 4

Chemical structure

Chemical structure of Triamcinolone Diacetate
A drawing shows what the molecule is, not what it does.

Existing / approved use

Documented · FDA, WHO, ChEMBL

Approved for

  • Airway obstruction
  • Eye inflammation
  • Hemorrhoid
  • Nasal congestion
  • Skin disease

Indications ChEMBL records as approved, from FDA and DailyMed labels. Label ↗

WHO therapeutic group
Corticosteroids for local oral treatment; Corticosteroids; Corticosteroids, moderately potent (group ii); Corticosteroids, moderately potent, other combinations; Glucocorticoids
Anti-infective classification
Not classified as an anti-infective.

Repurposing investigation

This medicine is being investigated here for AI-predicted antimicrobial activity against MRSA. It was surfaced computationally for further investigation; it is not an established treatment for this infection.

AI-predicted activity

AI prediction · nothing measured
  • MRSA53.5% AI-predicted activityAt or above the ≥40% mark this site uses to surface candidates.
  • E. coli30.6% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.
  • K. pneumoniae30.9% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.
  • M. tuberculosis28.8% AI-predicted activityBelow the ≥40% mark this site uses to surface candidates.

A model’s estimate of laboratory activity against each pathogen species. It is not clinical effectiveness.

Evidence

Clinical and experimental

Documented evidence

Clinical

50+registered studies name this medicine, for any condition. The registry search keeps the first 50, so there may be more. See them below.

Experimental

No evidence found

No laboratory measurement against the four pathogens in the ChEMBL records loaded here.

Open Triamcinolone Diacetate in ChEMBL Registered studies below

Docking

Computational · nothing measured

Dihydrofolate reductase ↗ (E. coli)

Not yet docked: queued in the docking rundetails

KPC-2 carbapenemase ↗ (K. pneumoniae)

-7.8 kcal/mol

0better fit →-12

Enoyl-ACP reductase (InhA) ↗ (M. tuberculosis)

-8.5 kcal/mol

0better fit →-12

Dihydrofolate reductase ↗ (MRSA)

-8.0 kcal/mol

0better fit →-12

AutoDock Vina, one experimentally solved protein per pathogen. This project’s screening target is -7.0 kcal/mol, its own mark rather than a universal cutoff. A docking score is a structural hypothesis, not proof of binding, and requires experimental validation.

Other medicines to investigate

AI prediction · nothing measured

Other repurposing candidates: approved medicines besides Triamcinolone Diacetate with AI-predicted activity ≥40% against the chosen pathogen, leaving out existing antimicrobials. They are computational candidates for further investigation, not alternatives and not recommendations.

Sorted by AI-predicted activity, high to low. The order is not a ranking of which medicine is better.

Registered studies

A registration describes a study; it does not establish a positive result.

  • Comparison of Topical Calcipotriol and Intralesional Steroids in Alopecia Areata

    NCT07453238 · start 2026-10-01

    Registered record
    Registry ID
    NCT07453238
    Conditions
    Alopecia Areata
    Interventions
    Calcipotriol; Triamcinolone Acetonide
    Study type
    INTERVENTIONAL
    Phase
    Phase 4
    Registry status
    Not yet recruiting
    Start
    2026-10-01
    Completion
    2027-03-01
    Enrolment
    60

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionAlopecia Areata
    InterventionCalcipotriol; Triamcinolone Acetonide
    PhasePhase 4
    Registry statusNot yet recruiting

  • Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn Scars

    NCT07660120 · start 2026-08-22

    Registered record
    Registry ID
    NCT07660120
    Conditions
    Burn; Hypertrophic Scars; Scar Improvement by Laser; CO2 Laser in Scars
    Interventions
    Fractional Ablative CO₂ Laser; Triamcinolone Acetonide; Fluorouracil (5-FU)
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Not yet recruiting
    Start
    2026-08-22
    Completion
    2028-07-10
    Enrolment
    65

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionBurn; Hypertrophic Scars; Scar Improvement by Laser; CO2 Laser in Scars
    InterventionFractional Ablative CO₂ Laser; Triamcinolone Acetonide; Fluorouracil (5-FU)
    PhaseNot applicable
    Registry statusNot yet recruiting

  • Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

    NCT07352566 · start 2026-08-01

    Registered record
    Registry ID
    NCT07352566
    Conditions
    Psoriasis; Atopic Dermatitis
    Interventions
    In situ cutaneous microdevice; Triamcinolone; 5-Fluorouracil; Calcipotriene; Tapinarof; Crisaborole; Tacrolimus; Adalimumab; Etanercept; Certolizumab; Infliximab; Secukinumab; Ixekizumab; Apremilast; Risankizumab; Ustekinumab; Hydroxychloroquine; Methotrexate; Mycophenolate; Azathioprine; Chloroquine; Cyclosporine; Tofacitinib; Deucravacitinib; Dupilumab; Tralokinumab; Guselkumab; Tildrakizumab; Baractinib; Abrocitinib; Upadacitinib; Lebrikizumab; Nemolizumab; Ruxolitinib; Bimekizumab; Roflumilast
    Study type
    INTERVENTIONAL
    Phase
    Phase 4
    Registry status
    Not yet recruiting
    Start
    2026-08-01
    Completion
    2030-06-01
    Enrolment
    10

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionPsoriasis; Atopic Dermatitis
    InterventionIn situ cutaneous microdevice; Triamcinolone; 5-Fluorouracil; Calcipotriene +32 more
    PhasePhase 4
    Registry statusNot yet recruiting

  • Adjuvant Steroid Outcomes in Idiopathic Subglottic Stenosis

    NCT07228104 · start 2026-05-20

    Registered record
    Registry ID
    NCT07228104
    Conditions
    Idiopathic Subglottic Stenosis
    Interventions
    Triamcinolone 0.1%; Placebo
    Study type
    INTERVENTIONAL
    Phase
    Phase 3
    Registry status
    Recruiting
    Start
    2026-05-20
    Completion
    2032-01
    Enrolment
    226

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionIdiopathic Subglottic Stenosis
    InterventionTriamcinolone 0.1%; Placebo
    PhasePhase 3
    Registry statusRecruiting

  • One Cause of Heel Pain is Plantar Fasciopathy (PF). In Most Cases, a Heel Spur is Frequently Present Alongside PF. We Aim to Evaluate the Efficacy of Corticosteroid Injection and Radiofrequency Ablation, Along With Tissue Elasticity Assessed by Ultrasound, in Patients With Chronic Pain (≥6 Months).

    NCT07120204 · start 2025-08-15

    Registered record
    Registry ID
    NCT07120204
    Conditions
    Plantar Fasciopathy; Chronic Pain; Corticosteroid Injection; Radiofrequency Ablation; Elasticity Imaging Techniques
    Interventions
    Corticosteroid Injection; Radiofrequency thermocoagulation
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Not yet recruiting
    Start
    2025-08-15
    Completion
    2026-08-15
    Enrolment
    50

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionPlantar Fasciopathy; Chronic Pain; Corticosteroid Injection; Radiofrequency Ablation +1 more
    InterventionCorticosteroid Injection; Radiofrequency thermocoagulation
    PhaseNot applicable
    Registry statusNot yet recruiting

  • Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Recurrent Aphthous Stomatitis

    NCT06993337 · start 2025-06-15

    Registered record
    Registry ID
    NCT06993337
    Conditions
    Recurrent Aphthous Stomatitis
    Interventions
    35% Topical Bromelain in Orabase; 50% Topical Bromelain in Orabase; 0.1% Topical Triamcinolone Acetonide in Orabase
    Study type
    INTERVENTIONAL
    Phase
    Phase 2
    Registry status
    Not yet recruiting
    Start
    2025-06-15
    Completion
    2026-06-15
    Enrolment
    63

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionRecurrent Aphthous Stomatitis
    Intervention35% Topical Bromelain in Orabase; 50% Topical Bromelain in Orabase; 0.1% Topical Triamcinolone Acetonide in Orabase
    PhasePhase 2
    Registry statusNot yet recruiting

  • Comparison of Triamcinolone Injection and TENS for Long Head of the Biceps Tendinopathy

    NCT07817433 · start 2025-01-06

    Registered record
    Registry ID
    NCT07817433
    Conditions
    Long Head of Biceps Brachii Tendinopathy
    Interventions
    Transcutaneous Electrical Nerve Stimulation (TENS); Triamcinolone Acetonide and Lidocaine Hydrochloride
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2025-01-06
    Completion
    2026-02-11
    Enrolment
    42

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionLong Head of Biceps Brachii Tendinopathy
    InterventionTranscutaneous Electrical Nerve Stimulation (TENS); Triamcinolone Acetonide and Lidocaine Hydrochloride
    PhaseNot applicable
    Registry statusCompleted

  • INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE

    NCT06700109 · start 2024-11-19

    Registered record
    Registry ID
    NCT06700109
    Conditions
    Osteoarthritis (OA) of the Knee
    Interventions
    Neural Ice; Triamcinolone acetate
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Active not recruiting
    Start
    2024-11-19
    Completion
    2027-02-01
    Enrolment
    263

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionOsteoarthritis (OA) of the Knee
    InterventionNeural Ice; Triamcinolone acetate
    PhaseNot applicable
    Registry statusActive not recruiting

  • Comparative Evaluation of Three Pulpotomy Agents for Permanent Mature Molars With Irreversible Pulpitis

    NCT06232941 · start 2024-04-01

    Registered record
    Registry ID
    NCT06232941
    Conditions
    Vital Pulp Therapy
    Interventions
    Full pulpotomy procedure
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Unknown
    Start
    2024-04-01
    Completion
    2025-12-01
    Enrolment
    36

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionVital Pulp Therapy
    InterventionFull pulpotomy procedure
    PhaseNot applicable
    Registry statusUnknown

  • Efficacy and Safety of Myopic Macular Hole Closure Surgery Without Endotamponade Agent

    NCT07129798 · start 2024-01-18

    Registered record
    Registry ID
    NCT07129798
    Conditions
    Macular Hole; Myopia
    Interventions
    ILM flap with no endotamponade technique
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Active not recruiting
    Start
    2024-01-18
    Completion
    2026-12-26
    Enrolment
    20

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionMacular Hole; Myopia
    InterventionILM flap with no endotamponade technique
    PhaseNot applicable
    Registry statusActive not recruiting

  • Effect of Irrigation of Triamcinolone Versus Hypertonic Saline in Decreasing Seroma Post Abdominoplasty

    NCT07733921 · start 2023-11-01

    Registered record
    Registry ID
    NCT07733921
    Conditions
    Seroma Formation
    Interventions
    Irrigation of Triamcinolone; Hypertonic Saline 10%; Control
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2023-11-01
    Completion
    2025-08-01
    Enrolment
    90

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionSeroma Formation
    InterventionIrrigation of Triamcinolone; Hypertonic Saline 10%; Control
    PhaseNot applicable
    Registry statusCompleted

  • Dexmedetomidine Versus Triamcinolone Treatment in Carpal Tunnel Syndrome

    NCT05624866 · start 2022-10-10

    Registered record
    Registry ID
    NCT05624866
    Conditions
    Carpal Tunnel Syndrome
    Interventions
    Dexmedetomidine; Triamcinolone
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Unknown
    Start
    2022-10-10
    Completion
    2023-12-10
    Enrolment
    60

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionCarpal Tunnel Syndrome
    InterventionDexmedetomidine; Triamcinolone
    PhaseNot applicable
    Registry statusUnknown

  • Comparison of Chitodex Gel Vs NexFoam on Post-operative Outcomes in the Treatment of Chronic Rhinosinusitis

    NCT05083741 · start 2021-12-27

    Registered record
    Registry ID
    NCT05083741
    Conditions
    Chronic Rhinosinusitis
    Interventions
    Chitogel; Nexfoam
    Study type
    OBSERVATIONAL
    Phase
    Not recorded
    Registry status
    Terminated
    Start
    2021-12-27
    Completion
    2024-08-08
    Enrolment
    7

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionChronic Rhinosinusitis
    InterventionChitogel; Nexfoam
    PhaseNot recorded
    Registry statusTerminated

  • Macular Micro Vascular Changes Following Macular Hole Repair : Optical Coherence Tomography Angiography Study

    NCT06233500 · start 2021-12-01

    Registered record
    Registry ID
    NCT06233500
    Conditions
    Macular Holes
    Interventions
    pars plana vitrectomy
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Unknown
    Start
    2021-12-01
    Completion
    2024-03-15
    Enrolment
    28

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionMacular Holes
    Interventionpars plana vitrectomy
    PhaseNot applicable
    Registry statusUnknown

  • Photobiomodulation and the Intralesional Administration of Corticoid in the Keloid Surgery.

    NCT04824612 · start 2021-08-30

    Registered record
    Registry ID
    NCT04824612
    Conditions
    Keloid; Cicatrix
    Interventions
    Photobiomodulation with blue led; Triamcinolone Hexacetonide; Sham LED
    Study type
    INTERVENTIONAL
    Phase
    Not applicable
    Registry status
    Completed
    Start
    2021-08-30
    Completion
    2023-11-30
    Enrolment
    4

    As stored from ClinicalTrials.gov. Registration describes a study; it does not mean the study worked.

    ConditionKeloid; Cicatrix
    InterventionPhotobiomodulation with blue led; Triamcinolone Hexacetonide; Sham LED
    PhaseNot applicable
    Registry statusCompleted